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Some of people are born with a deficiency in the production of DAO,
which causes us to not be able to
breakdown histamine properly. This results in excess histamine in the body, which can wreak havoc and cause symptoms such as bloat, feeling excessively full after eating or drinking, diarrhea, abdominal pain, itchiness, hives, flushing, congestion, headache, dizziness, fast heart rate, and anxiety. Additionally, deficiencies of copper,
vitamin C, and pyridoxine can also result in reduced activity of DAO. And, fascinatingly enough, the phase of the menstrual cycle can also affect how effective DAO is at breaking down histamine in our gut. [5]Living with a Histamine IntoleranceA histamine intolerance is in no way a lifelong sentence to spending all your time and energy avoiding high histamine foods. The key is to find someone educated in all of these factors affecting how your body deals with histamine, who can help you investigate where your histamine intolerance is coming from. The solution could be as easy as adding a DAO supplement to your diet. [6] It could also mean digging into your gut microbiome health and exploring what has affected it, such as toxins like mold, heavy metals, parasites, or Lyme Disease. [7]If you have a chronically inflamed gut, this could mean finding out what is driving that inflammation. It could also mean tuning down and calming your nervous system, which can be the source of sensitivities like histamine intolerance. Genetic
testing can even be done to determine if you have an SNP, a genetic variation, which causes you to produce less DAO.